If you are at all familiar with psychedelics, you have most likely come across the idea of “set and setting.” This proverb contains a great deal of wisdom because it serves to remind (or warn) psychonauts that preparations are required if they want their journey to go smoothly. How Long Until The Effects Of Mushrooms Start? If you eat mushrooms whole, it usually takes about 30 minutes for them to start working. Though sometimes it takes up to an hour, you can begin to feel the effects of mushrooms in as little as ten minutes. Usually, the come up lasts for two hours, the peak occurs three to four hours…